Question for those who have used Mutaflor / e.coli Nissle 1917 probiotic

Hi Probiotic,

I tried it for two weeks no improvement at all. I was so expensive too. I'm just working with Nuticology's Perm a vite and another flora probiotic. I'm going to do a probiotic enema tonight and see if it helps, I've done them in the past, no help that I noticed. Colozal seems to be helping. You sound like me we try something, stop and go back to it right? We are trying so hard to see what works and what will stick!

I agree with lookforcure, I may try it again too. I forget sometimes that D can be a good sign of things existing the body.

Journeytoheal,
I have posted this info on another thread but I think you and other people need to know this. Before you take a trip to Canada, you might need to consider to take Prescript Assist soil based probiotic. I took Mutaflor, it is an excellent probiotic fro UC. I had a long remission thanks to it while I was on it. Prescript Assist works differently than Mutaflor but there is a lot of research behind it too.
Not many peple heard about it. You do not need to refrigerate it and these bacteria will not die because of the stomach acid. I took it for a while and still have 3 bottles for the future.
Here is some information about it.
Prescript-Assist Probiotic is backed by five years of scientific, doctor-lead, double-blind, peer-reviewed clinical studies. These clinical studies indicate that the unique Probiotic – Prebiotic blend of Soil Based Microorganisms (SBO) found only Prescript-Assist outperformed other popular Probiotics (including Lactobacillus and Bifidobacterium).

Advantages of Prescript-Assist:
•Better survival in the gut
•Out-competes established negative bacteria
•Improves immune system
•Breaks down toxic chemicals

Prescript-Assist Clinical Studies Indicated Scientifically Significant Reduction in the Following Diseases and Symptoms:
1.Irritable Bowel Syndrome (IBS)1,2
2.Nausea1
3.Indigestion / Flatulence14. Colitis1,2
4.Antibiotic Induced Gastritis (during antibiotic therapy)2
5.GI Tract “Reconditioning” (post-antibiotic therapy)2
6.Diverticulosis2
7.Chrohns2
8.Vaginitis2
9.GERD2
10.Human Bacterial-Diarrhea (the most aggressive diarrhea caused by bacteria associated with 3rd world countries)3

http://www.perfectsupplements.com/v/ClinicalExp.pdf
http://www.perfectsupplements.com/v/IBS.pdf
http://www.perfectsupplements.com/v/Diarrhea.pdf
http://www.ncbi.nlm.nih.gov/pubmed/16117982

I have kept my expired mutaflor in the fridge all this time... Am thinking about the prescript assist too (I do use primal defense on and off, it certainly seems another decent eniugh SBO) - my biggest, concern with Prescript Assist is that it contains prebiotics. Prebiotics have always been an issue for me in the past. If I do try mutaflor again, I woukd certainly do the 1 cap oer 3 days initially. unfort. it's not possible to break up capsules since they are hard shell enterically coated and sealed.

Does anyone know what stores sell mutaflor? I live right on the border and can easily drive across the border to pick some up.

Hi there,

I've tried Mutaflor a number of times and while it alone won't get me into remission, it seems to do a decent job of keeping me there once I've reached remission. I have big issues with compliance, so at one point or another, I always fall off the meds wagon. It's also kind of a pain to keep up - pricey and the whole 'must stay cooled' thing.

I never noticed any gas, diarrhea or the like while on it, though I've been told (and the instructions suggest) to start slow in case you do get uncomfortable symptoms.

I took E. Coli Nissle in Mutaflor for over a year before the FDA banned sales in the U.S. I found it helpful but not more so than VSL#3DS or Culturelle. Those are my two favorites. Everyone is different so don't worry if a particular probiotic does not seem compatible with every individual.

This is from a very recent thread and may explain why a probiotic that works for one may not work for everyone else:

Imagardener2 said...
This article www.sciencedaily.com/releases/2011/04/110420143620.htm indicates that people may have different gut types, meaning different types of predominant bacteria in their gut.

Guys, I have found an interesting research about S. Boulardii.

..."Non-pathogenic yeasts present some characteristics
that differentiate them from other probiotics. The natural
resistance they have to antibiotics has constituted an
interesting basis for their application as probiotics. In
this regard, Saccharomyces boulardii was the most widely
tested in experimental and clinical assays, showing very
important results.
This microorganism was initially isolated from Indochinese
fruits (lychee). Fruits contaminated with Saccharomyces
boulardii were used in the local popular medicine
for the treatment of diarrhea. A product containing
this microorganism was introduced in France with the
same objective in 1950, and in the present days (Ultralevure,
Biocodex, Monterouge, France) it is widely commercialized
in European, African, and South American
countries. It is generally administered in lyophilized
powder, corresponding to approximately 3·1010 cells/g.
Unless exogenously administered, S. boulardii is not found
as part of the intestinal microflora of laboratory animals
or of humans, and under normal conditions, it does not
permanently colonize the gastrointestinal tract when
orally administred, and is eliminated within 24–72 hours
if not reinoculated (10).
The pharmacodynamics of S. boulardii involves three
different aspects: (i) a direct antagonistic effect on enterobacteria
and other yeasts, (ii) an antisecretory effect
by acting specifically on the binding of toxins to intesnal receptors, and (iii) a trophic effect by stimulating enzymatic
activities and intestinal defense mechanisms
(11). Besides, S. boulardii can also destroy the receptor
site for Clostridium difficile toxin A and B by producing
protease (12), it is thermotolerant and grows at the unusually
high temperature of 37 °C. The taxonomy of the
genus Saccharomyces based on phenotypic and genotypic
methods has been revised several times over the years
and now, using microsatellite polymorphism typing, allows
to discriminate S. boulardii from other strains of S.
cerevisiae (13). In contrast to lactic acid and bifidobacteria,
S. boulardii is naturally resistant to antibiotics (14)."...

From:
http://www.ftb.hr/files/journals/1/articles/694/public/694-686-1-PB.pdf

You can get S. Boulardii 90 cap. for $20-$30, depending on the brand. It is much cheaper then Mutaflor, Prescript Assist, Dr. Ohhira or VSL.

Just one thing you need to know. Not everybody can tolerate well this probiotic. It is yeast, so it can cause gas, bloating, diarrhea, cramps..
It did not "agree" with me personally and I know a few people on this forum had the same problem with this probiotic. Also, because it is yeast probiotic there is more chances for a bad reaction to it.
I think you need to know this. Comparing to Mutaflor, I do not know anybody who actually went into remission just thanks to S. Boulardii. Mutaflor on the other hand, can put a person with UC in remission.
I am one of these people.

Probiotic,
I have never heard of or seen online Mutaflor Mite. It might be hard to get, even harder than regular Mutaflor. If they have it somewhere it is probably in Gemany, where Mutaflor is made.
It is so annoying that FDA had to stick their nose and stop the selling of Mutaflor in the USA. They did a big disservice to a lot of sick people.

Just in case anyone is able to get their hands on some mutaflor suspension from Germany or figure out a way to use the pills to make this, apparently mutaflor can be cultured at home just like yogurt! I haven't tried this but it sounds a whole lot cheaper.

http://www.drmyhill.co.uk/wiki/Growing_Mutaflor