Doctor just increased enema's to two per day

My son is 8 years old and was Diagnosed with UC in December, 2011. He is on Pentasa (3 pills per day), Azathioprine, Nexium and a mesalamine enema before bed. He recently had a flare after being in remission for only 3 months. The doctor did a sigmoidoscopy and found the inflamation is low in his colon. Therefore, the doctor wants us to try a second enema during the day. Does anyone have any ideas on when it would be best to give the second enema. The first is given right before bed 9:00 p.m. Currently I'm giving him the second one at about 1:00 p.m. in the afternoon. He is homeschooled and always lays down to read between 1:00-2:00 p.m. so that is why I am giving him one at this time. It has never been an issue for him to retain the enema. I am wondering if it would be better to give him the second enema right after he wakes up in the morning. Anyone have an ideas?

     My heart goes out to your son.  This disease is horrible but devastating to one so young.  When I suffered with UP, I did the enemas before going to bed and first thing in the morning.  I do hope your son goes into remission real soon.

Thanks so much for the information. I am going to check with his Doctor and see if Pentasa is the best medication for him to be on since we found out that the disease is lower in the colon. He is on 1500 mg a day and he takes a pill in the morning, afternoon and evening. The lower dose is based on his weight, 65 lbs. I asked the doctor about increasing his dose, but the doctor said he would probably start getting headaches. I am going to check into the other medication that someone mentioned is better for the lower colon.

Based on your responses, I will try doing the second enema earlier in the morning. Does anyone think it is beneficial for him to be laying down reading for about an hour after the enema? My theory is that it might absorb into him better and be able to be more effective? I can't ask the doctor these kinds of questions, he is so busy that I have to stick with the more important things and sometimes can't even get all those questions answered.

This forum has been so helpful to us. My son became sick during the first week of December. I took him to a total of 4 pediatricians, two urgent care visits and one day spent in the emergency room. He still wasn't diagnosed! They thought he had some bacteria infection or parasite and kept sending us home to do more stool samples. I was back and forth to the hospital doing stool samples for 3 weeks, meanwhile he kept having terrible stomach cramps and losing weight. After searching the web for information, I stumbled upon your forum and actually decided that he might have UC. I took him back to the pediatrician and told him what I thought. The pediatrician didn't think he had UC because we don't have any history in our family of it. By this time, my son had
lost 15 lbs. and was anemic. We ended up taking him to the children's hospital and finally he was diagnosed with UC. Had to spend 10 days in the hospital over Christmas and he had to have a blood transfusion. This little boy is so tough to have gone through all this. He is doing better now, but I am very nervous about getting this under control. 6 months to the day we went into the hospital he did a kids triathlon and won first place in his age group. But only two weeks after the triathlon things started to go downhill with a flare. This disease has a mind of its own!

I got a book from the library..."The Inside Tract" by Gerard E. Mullin, MD. Very useful info regarding supplements and diet.