I am just finishing my fourth week of Uceris after colonoscopy showed some inflammation in the transverse and right side - I wasn't even aware of it, didn't have significant symptoms other than some gas (with pains across the midsection occasionally) and some moderate urgency.

After a week I noticed the gas had lessened considerably and now it's gone, along with the pains. And yesterday I realized the urgency was a lot less.

I continued the steroid enemas for the first 3 weeks and have been tapering those.

Possible side effects: about three days ago I noticed a metallic taste in my mouth. I had tried a new protein powder in my morning smoothie and thought maybe it was some ingredient in that - but I think it's the Uceris. And, not sure if this is related, three times I've had a pain in the middle of my back, a sharp pain that has lasted 2 -3 minutes and gone away. It has happened while I have been doing nothing in particular; standing and talking to someone. Had a minor sensation of it last night in the wee hours when I woke up.

The only other different thing I am noticing: perhaps I am a bit more moody than usual? Or maybe it's just life. My cat, who turned 20 this month (!!) died a few days ago, and although she lived a good long life, etc, I am sad to be without her. The house feels quieter without her, somehow, even though she was not necessarily noisy these last months. So, grief is a funny thing, comes in waves.

I am happy to hear it's helping your symptoms. I never had a metal taste with uceris but I had it with Flagyl. I guess it's one of those weird things that different meds can cause :( Maybe it was the protein shake? Hopefully you get to the bottom of it soon. I am sorry about your cat. So sad. No matter what age, it's never enough...

I took Uceris for 2 months. No side effects at all.

Very sorry about your cat.

Songlady, sad to hear about your sweet kitty...my deepest condolences. I know the loss and the silence can be deafening. Hugs

How long will you be on the uceris? And when do you see your doc next? Good to hear you're having improvement...sucks about the side effects.

q

Sorry I can't comment on Uceris, but like Notso, I do know the metallic taste from Flagyl, yuck! (Nothing helped me to chase that while on the drug, except for marinara sauce, bad for active UC!) In case you also have dry mouth, you could try Biotene mouth rinse (otc) for help. *** RE your cat, I can totally empathize. I knew a wonderful 20 yr-old ultimately done in by failing kidneys, though he still loved to watch birds from the living room window sill 'til nearly the last couple hours he lived. His favorite food was roast turkey, so for him, Thanksgiving Day was like catnip=ecstasy!

The only other thing is that I bought a different brand of protein powder for my morning smoothies. To be sure, at first I thought the protein was the cause of this, because the taste started the morning of my first smoothie with the new powder.

But I have not used it consistently each day since, just on the chance. Maybe I will go back to the old protein for a week and see what happens?

I was on on pred only once, for 2 years, but I was off it by 1988. I do not remember metallic taste being an issue; and though it was years ago, I think this would have stuck in my mind.
OK, maybe it's the protein!