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LDN has stopped blood and stopped severe flare

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Ulcerative Colitis
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Posted 7/12/2016 8:29 PM (GMT 0)
Remicade is stronger in affect than mesalamine. It's a potent, strong medication.

The only side effect that matters is the one you get, not what's listed on the insert. I've gotten no side effects from any of the various tiers of uc medications, mesalamine, immunomodulators, or biologics. Well not including corticosteroids, as everyone gets side effects from the dreaded pred.

I would place diet modifications as mild in affect, as well. I'm willing to bet there's few cases were a diets only put someone in remission when biologics didn't.

I think to be the most helpful, it's good to take the patient's severity into account as to when it might be the most effective. Diets and LDN work for some, but could we instead say whom it's most likely to help? To me, that'd be the most beneficial. Take me as an example, remicade is the only thing that touches my uc, strongest treatments only.
Posted 7/12/2016 4:11 PM (GMT -5)
ya, well the point i'm trying to make (or points) is biologics are not a stronger anti-inflammatory - they are a completely different class of drugs - it's just semantics, but my point is being missed i think -

i didn't need STRONGER drugs, i needed a better treatment - some folks have and will make the choice to stick with pharma meds in lieu of a drastic lifestyle change - i think that's just fine - but to say that someone who has not had success with tier 1 drugs needs to move onto tier 2 is just wrong - there are too many treatment options out there -

did you try LDN ?
Posted 7/12/2016 6:51 PM (GMT -5)
i'm not so much into conspiracy theories but i've recently read a very appealing article in the Polish medical press which claimed that ldn is such a miracle drug, still undiscovered fully possibly because the big pharma fears its potential to cure so many diseases including cancer (this one is also interesting http://whitakerwellness.com/health-concerns/autoimmune-conditions/naltrexone/
Posted 7/12/2016 6:56 PM (GMT -5)
Remicade is a powerful anti-inflammatory agent, binding and inactivating signalling molecules that drive inflammation.
The mechanisms for LDN are far less clear. It is suspected that the body increases opioid production when uptake receptors are inactivated (by a low dose of naltrexone). However it is also speculated that the behavior of glial cells, which are part of the nervous system, are altered.

Its not about one treatment being 'better' than the other, but it is important to appreciate the type of information being presented.
Posted 7/12/2016 8:39 PM (GMT -5)
I think the "some choose pharma in lieu of dramatic lifestyle changes" is a bit untrue, at least for me, anyways. I struggled for 8 months trying various diets and supplements before remicade. Remicade worked, the alternatives didn't. It's not a matter of a choice between an apple or an orange that anyone can make, it's all about what works for an individual and what doesn't.

I'm guessing that there is a variant of uc that responss to diet modifications and one that doesn't. Or that the diet modifications are just much weaker of an action than the biologics are.

Biologics have a strong anti-inflammatory affect, not a matter of symantecs. Different mechanism of action in each class of medications, but same result = less inflammation.
Posted 7/14/2016 10:18 AM (GMT -5)
I think the strength of any treatment is a matter of relativity. The way I see it my own treatment requires self-discipline, mental and physical perseverence and I can hose down flares - literally, starting with a homemade saline water enema followed by lglutamine/lactoferrin boost - that would earlier floor me in a matter of days.

The tier is based on levels of aggressiveness, a different ball game, so biologics is considered a more 'aggressive approach' compared to mesalamine due to potentially more hazardous side effects given it is an immunsupressor. So strength comes from success. In that LDN qualifies as an equally strong treatment for the original poster.

Post Edited (isleman) : 7/14/2016 9:27:41 AM (GMT-6)

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