HealingWell
Search Close Search
☰

Pregnant & Flare

Support Forums
>
Ulcerative Colitis
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
Posted 5/29/2017 8:02 PM (GMT -5)
Hi,

I'm 10 weeks pregnant and experiencing horrible flare for past one week. My current maintenance medications are 3.6 mg Mezavant and 75mg Imuran. Since flare started, doctor asked me to go on Prednisone but I requested for Cortenema to avoid taking prednisone before 13 weeks. But Cortenema is not working, what are my options? I feel my inflammation is higher near rectum area. OD you think Budenofalk rectal foam will be beneficial?
Posted 5/30/2017 7:42 AM (GMT -5)
You can up your mesalamine to 4.8 g a day, I would alternate rowasa and cortenema as well. Maybe even do one in the am and 1 in the pm. Pregnancy is so hard on our bodies, even without UC. I'm pretty sure totesmagotes started remicade while pregnant with her last baby.
Hang in there!
Posted 5/30/2017 10:23 AM (GMT -5)
If you want avoid systematic prednisone then you could consider a delayed-release steroid like clipper/entocort ec/uceris/. They're all generally not nearly as strong as prednisone is, and there's a point where prednisone becomes necessary. Try and see.

I don't see a rectal-route mesalamine mentioned, ask for a salofalk/pentasa/rowasa enema.

That's a very low dose of imuran/aza, 150 to 200mgs would be a more typical dose. Why is it so low?

Mezavant doses are generally lower and 3.6 grams a day might indeed be the maximum. Ask your doctor or pharmacist to see if a dose increase is possible.
Posted 5/30/2017 1:20 PM (GMT -5)
I was on 4.8 g Mezavant initially before going down to 2.4 maintenance dose.

Oh, but I wasn't pregnant!
Posted 5/30/2017 7:49 PM (GMT -5)
Forgot to mention, I was also on pentasa enema every 2 days as well. I was on 100mg Imuran it started to cause immune suppression that's why doctor reduced it to 75mg. I had a miscarriage (not related to uc) last year which led to huge flare since then mezavant or pentasa enema doesn't do anything for me. I'm on them to reduce cancer risk. Budenofalk rectal foam is what helped me to bring remission.

I felt really great at the beginning of the pregnancy. Flare started since catching a flu. Entocort seems good idea. Anyone else with similar experience?
Posted 6/2/2017 1:11 PM (GMT -5)
Hi sweety. Congrats on the pregnancy!

I flared really bad during my second pregnancy. Like momto2boys said I had to start remicade at 30 weeks. My flare started at 26 weeks and we couldnt get it under control even with 40 mg of pred. I was terrified to go into preterm labor so I made a had decision. It put me into remission prior to giving birth so for me it was the best decision for myself and baby.

I've tried Entocort and Uceris (while not pregnant) but they didn't help. Pred usually doesn't help me either but with my last couple mild flares its gotten things under control.

From what my GI says you and the baby are safe under 30 mg of prednisone. Higher doses pass through the placenta. I understand exactly how you feel though and don't want you to think I'm discounting that. Its very hard to make decisions on meds when you are carrying another human.

In my humble opinion I would do anything to get it under control now. If the cortenemas aren't helping I would ask for a blast taper...maybe starting at 20mg and see if it helps and taper quickly (like every 5 days) if your body will cooperate.

Also keep in mind that your hormones are going to shift towards the beginning of the second trimester and that could possibly stop the flare.

If you have any questions about my experience with my second baby and my meds please feel free to ask. I try to be an open book with my UC roller coasters to help others smile
✚ New Topic ✚ Reply