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Is anyone on Humira and methotrexate or Remicade and methotrexate?

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Ulcerative Colitis
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Posted 12/19/2011 6:45 PM (GMT -5)
Not doing so well on the maintenance dose of Humira. I am rapidly running out of options. So we are increasing my Humira to weekly for 3 mos and then adding methotrexate so hopefully after the 3 mos the metho has kicked in and I will be on the metho and bi weekly Humira.

I have avoided Methotrexate before and I am really nervous about adding it. Anyone on it with a biologic? Is it helping? Any side effects?
Posted 12/19/2011 11:08 PM (GMT -5)
Did you ask on the Crohn's board? I think both of those medications are more commonly used with Crohn's.
Posted 12/20/2011 3:03 AM (GMT -5)
My mom has Rheumatoid arthritis and she takes methotrexate and does Remicade infusions as well. She has no side effects from either one.
Posted 12/20/2011 3:51 PM (GMT -5)
I am on both MTX and weekly humira. I can say, it is helping my arthritis more than it is the UC. No side effects with the humira, but it does take a while for you to get used to the methotrexate. Key to it is, is to take it right before you go to bed, so you sleep most of the side effects away. You still wake up with the feeling of a hang over though. It does get better in time, so hang in there.
Posted 12/20/2011 9:41 PM (GMT -5)
For those of you on MTX or with family on MTX is it expensive? I know it has been around awhile so I am hoping not. My prescription insurance right now isn't the best and I can't afford another med if it is too much.
Posted 12/21/2011 10:03 AM (GMT -5)
It is not expensive at all. With my insurance, it only costs me $20
Posted 12/21/2011 10:19 AM (GMT -5)
Thanks Jano! Last question, do you take MTX by shot or pills? I knew a friend who was on it for something different than UC and she took pills. I know on the Crohn's board a few people take it by shot.

My doc mentioned we might start it as a shot and then go to pills, which seemed weird to me.
Posted 12/21/2011 3:40 PM (GMT -5)
I am on the pills. I heard the shot has less side effects. It is odd that he is doing the shot first. Usually the shot is given when the pills causes stomach upset or to alleviate some of the side effects. Also make sure you take 1mg of folic acid a day. MTX depleates your body of it and you need to replace it. Also folic acid eases some of the side effects too
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