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MTHFR/Methylation/Genetics/23 & Me?

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Ulcerative Colitis
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Posted 10/27/2017 7:07 PM (GMT -5)
Anyone here with U.C or even an IBD that has had experience with the MTHFR genetic defect and treating for it? I've been going down this path with 23 & Me but my local NP has never heard of it before. I'm curious if anyone knows of any docs in the Pacific NW area that may have experience with this?
Posted 10/28/2017 8:05 AM (GMT -5)
I know MTHFR mutations are much more common with uc patients. It affects Folic Acid levels in the body which is a type of B vitamin.

23andme had an interesting blog post on it. /blog.23andme.com/health-traits/our-take-on-the-mthfr-gene/

23andme said...
Some websites and products have made bold claims that common genetic variants in MTHFR can cause a wide array of health conditions, ranging from blood clots and cancer to autism and migraines.So we decided to dig deeper into the published scientific literature to evaluate the evidence.

Our conclusion?

Despite lots of research – and lots of buzz – the existing scientific data doesn’t support the vast majority of claims that common MTHFR variants impact human health.

Posted 10/28/2017 1:07 PM (GMT -5)
Thank you for bringing that up, iPoop. That does explain why I haven't found an awfully lot of people with U.C who are treating this, and similarly a lot of doctors.
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