ozanimod vs etrasimod

heya

Regular Member

Joined : May 2010

Posts : 144

Posted 5/14/2018 6:25 PM (GMT -5)

Ozanimod put back until next year.
Etrasimod is taking over the race.

https://www.investors.com/news/technology/biotech-stock-jumps-by-a-third-as-rivalry-with-celgene-heats/

Uniform Charlie

Veteran Member

Joined : Jul 2015

Posts : 1104

Posted 5/15/2018 11:22 AM (GMT -5)

Nice to see more drugs being developed. Mechanism seems to be different than others. Results were not very exciting though.

notsosicklygirl

Forum Moderator

Joined : Dec 2008

Posts : 17890

Posted 5/15/2018 11:27 AM (GMT -5)

I am always excited to see new options too. Thanks for sharing!

iPoop

Forum Moderator

Joined : Aug 2012

Posts : 16495

Posted 5/15/2018 11:34 AM (GMT -5)

Interesting, as it sounds like a different mechanism of action from other things available on the market for UC.

"Both drugs belong to a class called sphingosine 1-phosphate receptor modulators, or S1P, which are being tested in a number of inflammatory conditions. "

poopydoop

Veteran Member

Joined : Dec 2018

Posts : 2081

Posted 1/20/2019 7:03 AM (GMT -5)

Some new results for etrasimod:
http://www.spjnews.com/2019/01/09/arena-reports-positive-long-term-data-from-the-open-label-extension-of-the-phase-2-trial-evaluating-etrasimod-in-ulcerative-colitis/

Mechanism of action sounds a bit scary but I guess no worse than other immunomodulators!

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