There has been cursory evidence of PPAR-gamma agonists' usefulness in IBD. I have been watching it for a while but I do not find studies on humans but a lot on TNBS induced colitis in rats.
Plus, a while ago I came across something that said PPAR-gamma's expression is reduced in UC. Upping expression reduces TNF-a, IL-1b and IL-13, so in theory, one could achieve remission with standard UC meds and Actos.
https://www.europeanreview.org/wp/wp-content/uploads/8839-8848.pdfAnybody tried?