Somebody said...
Existing medications mainly act on the immune system and do not target epithelial regeneration. The mechanism of action of Indigo Naturalis (Qing Dai) differs from that of anti-inflammatory treatments, and, as a result, IN may be effective for refractory cases.
Somebody said...
Recent reports have indicated that IN induces critical adverse effects, such as liver dysfunction, severe colitis, and pulmonary arterial hypertension. To address these concerns, new medication needs to be developed by devising drug delivery system.
https://www.tandfonline.com/doi/full/10.1080/25785826.2019.1599158?scroll=top&needaccess=true