I would second mattam’s views above about where we are now in terms of systemic treatment… Bill...
My heartfelt condolences. I am so sorry for your loss…. Bill...
Just saw my first Pluvicto ad, aired during Bills/Broncos game. National ad, so some bucks behind this marketing campaign. Gaining traction among MOs, I guess....
Gallium might find something, but a stretch at these levels. F-18 unlikely though. If you can get insurance to go for it, no harm in looking. My oncologist likes to see much higher numbers before...
Brought tears to my eyes. Your story is the true definition of love… Bill...
I have been on 4 tablets, 160 mg total, from inception. Take them at 9 pm. Didn’t know also came in capsule format. I don’t like capsules either. … Bill...
You have had quite a haul in five years. I am happy for you that the Lupron/XTANDI double header is working for you. Best wishes… Bill...
ANB, That is a great start with the Pluvicto. If you do not have imageable mets, particularly to bone, you may anticipate getting a substantial long time benefit. Like all things PCa, the sooner a...
Down is always good with the beast… Bill...
This is such sad news. My condolences to Janice and Steve’s family. Steve was an inspiration to all of us and not only pioneered going where none of us had yet gone, but kept us informed with every...
Any links to reference to Alpha Emitters?...
If called upon to name a single factor in poorer life prospects, I would bet on plastics in all forms. Micro-plastics are everywhere and in each of us. Not many years ago I walked for miles along the...
Hi Gia777, Nothing unusual, just normal variability most likely. Good inputs above. For the long haul, I also am a perfect 4+4 Gleason 8. Had surgery in ‘09 and still here, 15 active and wonderful...
Cyclone — Floaters are very common.. I have had them for years before PCa came into my life. That said, I have noticed a steady deterioration in my night vision in recent years. Have some small...
Tend to think like mattam that once the disease is in us, diet choices probably will not matter much. I think of diet these days as more a matter of preference and what is enjoyable. For example, to...
An MO will give you the fullest chance to explore ADT options. IMHO, worth the drive if Mayo is your best bet a consult at a comprehensive cancer treatment center. If your disease is broadly...
1guyster, Our histories and current situation are very similar. I too am a perfect 4+4, metastatic, and been at this since surgery in ‘09. You asked about ADT options. I have just begun XTANDI mono...
After a six month Pause, I have started XTANDI mono therapy. Short leash. Assess in two months. Latest PSA 10.3; T is more or less No Where Man at 79. Good news is Gallium-68 PSMA PET last week came...
Doxa, I am sorry to read this. With multiple lesions, quickest response would obviously be ADT combining Lupron (probably) with one of the next generation medications. One anecdotal note: on my last...
JAMA reports a meta analysis reveals a twofold incidence of all CV (cardio) events associated with adding the newer generation of ARSIs to standard ADT. ARSIs include heavy hitters like Zytiga and...
“Favorable intermediate category?” I am not sure I would ever want to use the word “favorable” with respect to cancer. Nothing favorable about it. You have been very diligent with your urologists,...
Prato, In the last month my wife and I know six people who have come down with COVID. One 77 year old woman friend seemed impervious, always on the go, until she went to a wedding in New Jersey. She...
Prato, Congrats. Doing great. I am up for a three month draw at the MSK mother ship in Manhattan in two weeks. Get results in an hour or so as the draws are whisked by pneumatic tube (remember...
How do we know if 81’s entire post was not generated by his AI? I an thinking of delegating all my written coms to my AI avatar, known heretofore as NewspaperLover-2.1 (2.0 had a few flaws, unlike...
Recently read about an astonishing discovery at an ancient monastery in the mountains of Romania. The order of monks is nearly 1500 years old. The Rules of the Order have been handed down unchanged...
Great stuff, 81. I love this… Bill...
Since failed surgery in ‘09, I have had three distinctive rounds of ADT: in ‘11-‘12 as part of a salvage job, and in ‘21 and ‘23, always with Lupron in the fore. I have not experienced any untoward...
Your age works for you. I have a friend who underwent surgery at about your age. It took over a year, including Viagra, but he got it back. Wish you well… Bill...
BillyBob, The intermittent ADT described by mattam above in the EMBARK trial is me, real time right now. My MO placed me on the EMBARK ADT schedule last April, adding one month of Firmagon up front...
Hi Prato, Imperfect in terms of all mortality with associated PCa, but I am certain I would be long gone without the early warning system of PSA. Another consideration is that many forms of cancer...
Steve, Thank you for keeping us so well informed. We all hope that you can join the Actinium trial, and that results will be good. You are one of the stars for us long haulers. Best wishes…. Bill...
Mattam, Yeah, me too — born 12/02/1943. Extra month was nice. But when I have to scroll down forever to get to 1943 to indicate birth year on the Web for something or another, I’m thinking This Can’t...
Hi Mel, PSA rise upon stopping the Ogo should by itself not indicate resistance. Been my pattern for near a decade. If you want to do a PSMA scan for possible mets, recommend Gallium as opposed to...
Mc, Some solid histories already posted on this thread weighing experiences with both radiation and surgery as initial responses. As noted, it is a personal decision. I would add one thought. There...
A lot to discuss here at home. Me a Gleason 8 PCa patient starting 2009; my wife a triple negative BCa patient since 2003. Me, a patient at MSK since 2011; her, a 21 year survivor of triple negative...
So herself and I are currently doing a three week walkabout in England. Love Europe in March, as so many pleasures are indoors or at comfortable outdoor cafes. Also hate hot weather. London has been...
Hello Doxa, Sorry you and your husband have to be here. His history and mine are similar, DaVinci, followed by Salvage, now an imaged met years later. He and I started about the same time. In 2022 I...
PaxNova, If you can, on your next PSMA PET, gallium, as opposed to F-18, is now state of the art as an imaging agent. Nothing better than gallium — also you do not have to fast… Bill...
Hang in there PAX. Our histories and situations are remarkably similar, except I am older, though no wiser… Bill...
Halbert, Well written and a vital distinction… Bill...
JPS1, I transferred my case over to MSK in the fall of 2011, and have never looked back.That is 13+ years with a Gleason 8, and I am still there and very much alive. No miracles, but huge advantages...
I did a total right hip replacement while on ADT. My surgeon asked that my MO sign off, but that was it. Surgery and recovery time went great. Happy replacement… Bill...
Galileo, Good of you to drop in. Keep hanging in and hanging out. Best wishes… Bill...
Great that the Gleason remained steady, but I have also come to appreciate over the years that Gleason is not quite the whole story with PCa. The problem is that for myriad reasons, or for no...
Famed prostate cancer pathologist Jonathan Epstein has resigned from Johns Hopkins. He had been placed on administrative leave last year for unspecified reasons. For many years, and for many men on...
I’ve noticed a loss of distance in what used to be my favorite body part… Bill...
The food chain being as it is, all food is plant based, or going further, photosynthesis based. Herself and I eat a Mediterranean diet, which includes seafood and some poultry and red meat. But not...
Always good to be thankful, and maybe alert. I had right hip replacement surgery in the summer of 2021. My left hip had the same done in 2007. A got a little happy medicine before being wheeled into...
Jr, Sorry you had to join us. Seeds? You may want to weigh that approach against external beam radiation. Brachytherapy has been on the wane in recent years as external beam options have been...
hrpufnstuf, I use low dose Xanax also as the need arises, only occasionally, only at bed time — it helps eliminate those 3 am anxieties about PCa, that keep me awake, and have no resolution in the...